Viral infection


The viral infection model [1] is highly stochastic and extremely stiff. Moreover, all species present high variance and some species even have very high molecular populations. The model can be downloaded here. The reactions can be seen below. The rates are given in 1/day.

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A pruned abstraction of the system can be seen below. The state vector is [P, RNA, DNA].

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Please refer to the theory paper for more details.

Sources

[1] Srivastava, R., You, L., Summers, J., Yin, J.: Stochastic vs. deterministic modeling of intracellular viral kinetics. Journal of Theoretical Biology 218(3), 309–321 (2002)